In Hodgkin lymphoma, what distinctive cell type is typically present?

In Hodgkin lymphoma, what distinctive cell type is typically present?

• A. Reed-Sternberg cell
• B. Plasma cell
• C. B cell
• D. T cell

Answer: (A)

In Hodgkin lymphoma, the distinctive cell type that is typically present is the Reed-Sternberg cell. These are large, abnormal cells that are characteristic of Hodgkin lymphoma and serve as a key diagnostic feature. The presence of Reed-Sternberg cells helps differentiate Hodgkin lymphoma from other types of lymphomas and is crucial for accurate diagnosis. Reed-Sternberg cells originate from B lymphocytes, but their distinctive morphology and presence in the tumor microenvironment are what primarily define Hodgkin lymphoma. They are often multinucleated, giving them a unique appearance that pathologists recognize under the microscope. The other cell types listed, such as plasma cells, B cells, and T cells, are associated with different conditions or types of lymphomas, but they do not serve as identifying features for Hodgkin lymphoma. Plasma cells are typically associated with multiple myeloma, whereas B and T cells are more general categories of lymphocytes that can be present in various hematological diseases but are not specific markers for Hodgkin lymphoma.

In Hodgkin lymphoma, the distinctive cell type that is typically present is the Reed-Sternberg cell. These are large, abnormal cells that are characteristic of Hodgkin lymphoma and serve as a key diagnostic feature. The presence of Reed-Sternberg cells helps differentiate Hodgkin lymphoma from other types of lymphomas and is crucial for accurate diagnosis.

Reed-Sternberg cells originate from B lymphocytes, but their distinctive morphology and presence in the tumor microenvironment are what primarily define Hodgkin lymphoma. They are often multinucleated, giving them a unique appearance that pathologists recognize under the microscope.

The other cell types listed, such as plasma cells, B cells, and T cells, are associated with different conditions or types of lymphomas, but they do not serve as identifying features for Hodgkin lymphoma. Plasma cells are typically associated with multiple myeloma, whereas B and T cells are more general categories of lymphocytes that can be present in various hematological diseases but are not specific markers for Hodgkin lymphoma.