What are potential side effects of Carmustine?

What are potential side effects of Carmustine?

• A. Severe diarrhea
• B. Cardiac toxicity
• C. Renal toxicity/failure
• D. Anaphylaxis

Answer: (C)

Carmustine is an alkylating agent used in the treatment of various cancers, and it is known for its potential side effects, particularly those affecting the kidneys. Renal toxicity or renal failure can occur as a result of the drug's effects on the kidneys, which may lead to electrolyte imbalances and decreased kidney function. This side effect is significant because it can necessitate close monitoring of kidney function during and after treatment. The risk of renal toxicity with Carmustine is primarily due to its ability to interact with renal tubules, leading to damage. Patients receiving Carmustine may need regular assessments of renal function, including serum creatinine and electrolyte levels, to ensure that their kidneys are handling the medication appropriately. While it is true that other side effects may occur with Carmustine, such as severe diarrhea or cardiac toxicity, these are less prominent. Anaphylaxis is a rare and serious allergic reaction but is not specifically associated with Carmustine. Therefore, renal toxicity stands out as a well-documented and significant concern related to the use of this chemotherapy agent.

Carmustine is an alkylating agent used in the treatment of various cancers, and it is known for its potential side effects, particularly those affecting the kidneys. Renal toxicity or renal failure can occur as a result of the drug's effects on the kidneys, which may lead to electrolyte imbalances and decreased kidney function. This side effect is significant because it can necessitate close monitoring of kidney function during and after treatment.

The risk of renal toxicity with Carmustine is primarily due to its ability to interact with renal tubules, leading to damage. Patients receiving Carmustine may need regular assessments of renal function, including serum creatinine and electrolyte levels, to ensure that their kidneys are handling the medication appropriately.

While it is true that other side effects may occur with Carmustine, such as severe diarrhea or cardiac toxicity, these are less prominent. Anaphylaxis is a rare and serious allergic reaction but is not specifically associated with Carmustine. Therefore, renal toxicity stands out as a well-documented and significant concern related to the use of this chemotherapy agent.